Splanchnic Ischemia and Multiple Organ Failure

The Splanchnic Model of Multiple Organ Failure

Ischemia signifies failure to satisfy the metabolic needs of the cell secondary to either impaired oxygen delivery or the impairment of cellular oxygen extraction and utilization. Incomplete splanchnic cellular resuscitation has been associated with the development of multiple organ system failure and increased mortality in the critically ill patient (1,2). For many years, the merits of augment...

Nutrition and Multiple Organ Failure

Burn shock and multiple organ failure syndromes

Critical condition, developing in patients with burns during the burn shock more often produce the development of nonspecific reactions in the body, manifested as the system or the organ insufficiency and are determined by the term «syndrome of poly organ insufficiency» (SPOI). The course and treatment of 189 patients with burn shock have been analyzed. With the purpose of investigation all pat...

Pediatric septic shock and multiple organ failure.

In the last 5 years, the understanding of the epidemiology and pathogenesis of pediatric sepsis, septic shock, and multiple organ failure has expanded greatly. There has also been a substantial increase in the number of successful randomized trials in which success has been measured as reduction in mortality in adults, children, and newborns. This article discusses these advances, updating the ...

Diagnosis and management of splanchnic ischemia.

Splanchnic or gastrointestinal ischemia is rare and randomized studies are absent. This review focuses on new developments in clinical presentation, diagnostic approaches, and treatments. Splanchnic ischemia can be caused by occlusions of arteries or veins and by physiological vasoconstriction during low-flow states. The prevalence of significant splanchnic arterial stenoses is high, but it rem...